Questions people askOther medicines
The short answer
Yes: ezetimibe, bempedoic acid, and since 2026 Lipfendra (enlicitide), the first PCSK9 inhibitor taken as a daily pill.
Ezetimibe lowers LDL by about 20 to 25% on top of a statin and costs a few dollars a month. Bempedoic acid lowers it by about 17 to 23% and rarely causes muscle aches. Lipfendra lowers it much more and costs more.
Source: IMPROVE-IT, NEJM 2015; CLEAR Outcomes, NEJM 2023; US prescribing information.
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